Comparison of 5-Year Outcomes of Robot-Assisted Laparoscopic and Laparoscopic Partial Nephrectomy in Patients With Localized Renal Cell Carcinoma.
10.22465/kjuo.2017.15.3.172
- Author:
Chung Un LEE
1
;
Minyong KANG
;
Hyun Hwan SUNG
;
Hwang Gyun JEON
;
Deok Hyun HAN
;
Byung Chang JEONG
;
Seong Soo JEON
;
Hyun Moo LEE
;
Han Yong CHOI
;
Seong Il SEO
Author Information
1. Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. seongil.seo@samsung.com
- Publication Type:Original Article
- Keywords:
Renal cell carcinoma;
Robot-assisted laparoscopic partial nephrectomy;
Laparoscopic partial nephrectomy;
Oncologic outcomes;
Functional outcomes
- MeSH:
Carcinoma, Renal Cell*;
Follow-Up Studies;
Glomerular Filtration Rate;
Humans;
Intraoperative Complications;
Neoplasm Metastasis;
Nephrectomy*;
Recurrence;
Warm Ischemia
- From:Korean Journal of Urological Oncology
2017;15(3):172-177
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To compare the 5-year oncologic and functional outcomes of robot-assisted laparoscopic partial nephrectomy (RALPN) and laparoscopic partial nephrectomy (LPN) as treatment for localized renal cell carcinoma (RCC). MATERIALS AND METHODS: We analyzed the records of 181 patients with localized RCC who underwent RALPN (n=97) or LPN (n=84) between 2007 and 2011. Demographic and preoperative data with estimated glomerular filtration rate (eGFR), intraoperative data including warm ischemic time (WIT) and complications, oncologic outcomes (recurrence, metastasis), and rate of eGFR preservation at most recent follow-up were examined. RESULTS: WIT was shorter in the RALPN group (27±9.1 minutes) than the LPN group (31±10 minutes, p=0.019). Intraoperative complication rates were also lower in RALPN patients than LPN patients (4.1% vs. 14.3%). The eGFR preservation rate was higher in the RALPN group (84.6%) than in the LPN group (81.5%, p=0.049). Particularly, a relatively high difference in the eGFR preservation rate was observed in the RALPN group compared with the LPN group according to R.E.N.A.L. score 7–10 values (RALPN, 86.5±12.9 vs. LPN, 76.7±16.0; p=0.003). During the follow-up period, there was no local recurrence in either group and distant metastases only occurred in one patient in the RALPN group and in 2 patients in the LPN group. CONCLUSIONS: RALPN and LPN showed similar 5-year oncologic outcomes, but RALPN was superior to LPN in terms of WIT, intraoperative complications, and long-term eGFR preservation rate, especially in complex cases.
