Lobectomy versus Sublobar Resection in Non-Lepidic Small-Sized Non-Small Cell Lung Cancer.
10.5090/kjtcs.2017.50.6.415
- Author:
Min NAMKOONG
1
;
Youngkyu MOON
;
Jae Kil PARK
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Korea. jaekpark@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Lung neoplasms;
Thoracic surgery;
Pathology;
Lung lobectomy;
Pathology
- MeSH:
Carcinoma, Non-Small-Cell Lung*;
Humans;
Lung;
Lung Neoplasms;
Multivariate Analysis;
Pathology;
Recurrence;
Retrospective Studies;
Risk Factors;
Surgeons;
Survival Rate;
Thoracic Surgery
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2017;50(6):415-423
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Recently, many surgeons have chosen sublobar resection for the curative treatment of lung tumors with ground-glass opacity, which is a hallmark of lepidic lung cancer. The purpose of this study was to evaluate the oncological results of sublobar resection for non-lepidic lung cancer in comparison with lobectomy. METHODS: We conducted a retrospective chart review of 328 patients with clinical N0 non-small cell lung cancer sized ≤2 cm who underwent curative surgical resection from January 2009 to December 2014. The patients were classified on the basis of their lesions into non-lepidic and lepidic groups. The survival rates following lobectomy and sublobar resection were compared within each of these 2 groups. RESULTS: The non-lepidic group contained a total of 191 patients. The 5-year recurrence-free survival rate was not significantly different between patients who received sublobar resection or lobectomy in the non-lepidic group (80.1% vs. 79.2%, p=0.822) or in the lepidic group (100% vs. 97.4%, p=0.283). Multivariate analysis indicated that only lymphatic invasion was a significant risk factor for recurrence in the non-lepidic group. Sublobar resection was not a risk factor for recurrence in the non-lepidic group. CONCLUSION: The oncological outcomes of sublobar resection and lobectomy in small-sized non-small cell lung cancer did not significantly differ according to histological type.
