Aspirin and Non-steroidal Anti-inflammatory Drugs in Prevention of Gastric Cancer
- Author:
Yeon-Ji KIM
1
;
Woo Chul CHUNG
Author Information
1. Department of Internal Medicine, St. Vincent’s Hospital, The Catholic University of Korea College of Medicine, Suwon, Korea
- Publication Type:Review Articles
- From:
Journal of Digestive Cancer Report
2020;8(2):77-80
- CountryRepublic of Korea
- Language:English
-
Abstract:
Gastric cancer is one of the leading causes of cancer-related deaths worldwide. The increased expression of cyclooxygenase (COX)-2 has been implicated in the development and progression of gastric cancers. A number of recent studies have been published evaluating the chemopreventive effect of aspirin and non steroidal anti inflammatory drungs (NSAIDs) against gastric cancer. Aspirin and NSAIDs use may reduce the risk of gastric cancer incidence and death, whereas other studies have reported contradictory results. Therefore, further study should be needed to clarify the role of aspirin and NSAIDs in the chemoprevention of gastric cancer.
