Apathy: Neurobiology, Assessment and Treatment
10.9758/cpn.2021.19.2.181
- Author:
Mario FAHED
1
;
David C. STEFFENS
Author Information
1. Department of Psychiatry, University of Connecticut, School of Medicine, Farmington, CT, USA
- Publication Type:Review
- From:Clinical Psychopharmacology and Neuroscience
2021;19(2):181-189
- CountryRepublic of Korea
- Language:English
-
Abstract:
Apathy is a highly prevalent, disabling and treatment resistant syndrome. It is defined as a quantitative reduction of goaldirected activity in comparison to the patient’s previous level of in multiple dimensions including behavior/cognition, emotion and social interaction. It has been described in major depressive disorder, Alzheimer’s disease, frontotemporal dementia, Parkinson’s Disease, cerebrovascular disease, and vascular dementia, among others. This review will address the neuropsychology and associated neurobiological underpinnings of apathy in the above conditions, identify specific methods to assess apathy clinically, and review the literature on managing apathy across these various disorders.
