Clopidogrel-induced Spontaneous Spinal Epidural Hematoma.
10.3346/jkms.2007.22.3.577
- Author:
Jae Hoon SUNG
1
;
Jae Taek HONG
;
Byung Chul SON
;
Sang Won LEE
Author Information
1. Department of Neurosurgery, St. Vincent's Hospital, The Catholic University of Korea, 93-6 Ji-dong, Paldal-gu, Suwon, Korea. jaehoonsung@gmail.com
- Publication Type:Case Report
- Keywords:
Antiplatelet Agents;
Clopidogrel;
Spinal Epidural Hematoma
- MeSH:
Aged;
Brain/pathology;
Cerebral Angiography;
Female;
Hematoma, Epidural, Spinal/*chemically induced;
Humans;
Ischemia/drug therapy;
Magnetic Resonance Imaging;
Platelet Aggregation Inhibitors/*adverse effects;
Ticlopidine/adverse effects/*analogs & derivatives;
Time Factors;
Treatment Outcome
- From:Journal of Korean Medical Science
2007;22(3):577-579
- CountryRepublic of Korea
- Language:English
-
Abstract:
The hemorrhagic side effects associated with the use of clopidogrel are within the acceptable range and occur mainly at skin or gastrointestinal sites. We report a case of spontaneous spinal epidural hematoma (SSEH) in a 60-yr-old woman who was treated with clopidogrel for frequent transient ischemic attacks. To our knowledge, this is the second reported case of clopidogrel-induced SSEH. The patient's symptoms and past history of clopidogrel use suggested the diagnosis and made the procedure proceed quickly to operate SSEH 9 hr after the onset of paraplegia. The outcome was excellent. Therefore, with the popularity of antiplatelet prescription, physicians should keep in mind and urgently treat this unusual but critical side effect.
