The Association of Non-alcoholic Fatty Liver Disease and Physical Activity.
- Author:
Seong Hwan CHO
1
;
Sang Keun HAHM
;
Yu Na SEO
;
Ki Uk KIM
;
Jong Yong KIM
;
Jin A PARK
Author Information
1. Department of Family Medicine, Hanil General Hospital, Seoul, Korea. hahmsang@gmail.com
- Publication Type:Original Article
- Keywords:
fatty liver;
physical activity;
obesity
- MeSH:
Cholesterol, HDL;
Exercise;
Fasting;
Fatty Liver;
Fatty Liver, Alcoholic;
Glucose;
Hospitals, General;
Logistic Models;
Motor Activity;
Obesity;
Prevalence;
Triglycerides;
Surveys and Questionnaires
- From:Journal of the Korean Academy of Family Medicine
2008;29(7):513-519
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: There is an increasing interest in physical activity as a preventive and/or therapeutic option of non alcoholic fatty liver disease (NAFLD). The aim of this study was to examine the association between physical activity and ultrasound-diagnosed NAFLD. METHODS: From April to June 2007, 198 clients who had consumed alcohol less than 140 gram per week among 598 clients who visited a general hospital for medical check-up were enrolled in this study. Clinical, biochemical variables and physical activity were compared. Physical activity was measured by self-reported questionnaire using IPAQ-short form in Korean version. Multiple logistic regression analysis was used to identify independent association. RESULTS: The prevalence of NAFLD was significantly lower in the physical active group (more than 1500 MET- minutes per week) compared to the inactive group (9.6% vs 19.2%, P<0.05). This association was not attenuated when adjusted for age, BMI, HDL cholesterol, triglycerides, fasting glucose, and HOMA2-IR (Odds Ratio 0.23 [95% CI 0.07~0.77, P<0.05]). CONCLUSION: Compared to the physically inactive group, the risk of NAFLD was lower in the physically active group. Our data suggests that regular and moderate physical exercise can prevent the development of fatty liver disease.
