Efficacy of a Modified Pharmacomechanical Thrombolysis Technique for Endovascular Treatment of Thrombosed Prosthetic Arteriovenous Grafts.
10.3348/kjr.2012.13.3.300
- Author:
Sun Young CHOI
1
;
Byung Gil CHOI
;
Kum Hyun HAN
;
Ho Jong CHUN
Author Information
1. Department of Radiology and Medical Research Institute, School of Medicine, Ewha Womans University, Seoul 158-710, Korea.
- Publication Type:Original Article
- Keywords:
Hemodialysis access;
Prosthetic arteriovenous grafts;
Pharmacomechanical thrombolysis;
Urokinase;
Balloon angioplasty
- MeSH:
Adult;
Aged;
Aged, 80 and over;
Angiography;
Angioplasty, Balloon;
*Arteriovenous Shunt, Surgical;
Female;
Graft Occlusion, Vascular/*therapy;
Hemostatic Techniques;
Humans;
Male;
Middle Aged;
Polytetrafluoroethylene;
Proportional Hazards Models;
Radiography, Interventional;
Renal Dialysis;
Retrospective Studies;
Stents;
Thrombolytic Therapy/*methods;
Treatment Outcome;
Vascular Patency
- From:Korean Journal of Radiology
2012;13(3):300-306
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: We applied a modified pharmacomechanical thrombolysis (PMT) technique to endovascular treatment of thrombosed arteriovenous (AV) grafts without the use of any mechanical thrombectomy devices. The aim of this study was to evaluate the efficacy of the PMT technique in the treatment of thrombosed AV grafts by analyzing the long-term patency. MATERIALS AND METHODS: Eighty-two patients with thrombosed AV grafts were treated with the PMT technique. AV graft surveillance to detect failing/failed access was followed by endovascular treatment. RESULTS: The technical and clinical success rates were 95% and 95%, respectively. The total number of thrombolysis sessions was 279. A post-intervention primary patency rate was 45% and 22% at 12 and 24 months, respectively. The secondary patency rate was 96% and 91% at 12 and 24 months, respectively. No major complications were noticed. CONCLUSION: The modified PMT technique is effective in endovascular treatment of thrombosed AV grafts.
