Macrolide-refractory Mycoplasma pneumoniae pneumonia and hemophagocytic lymphohistiocytosis: case report and literature review
- Author:
Sung-Yun MA
1
;
Danbi KIM
;
Juyoung LEE
;
Kyoungsoon CHO
;
Jin-Soon SUH
;
Soo-Young LEE
Author Information
- Publication Type:Case Report
- From:Pediatric Emergency Medicine Journal 2020;7(2):145-150
- CountryRepublic of Korea
- Language:Korean
- Abstract: Mycoplasma pneumoniae causes various extra-pulmonary complications. As a rare but fatal hematological complication, hemophagocytic lymphohistiocytosis (HLH) can be observed in children with M. pneumoniae infection. We report a case of a 6-year-old girl with HLH who was initially presumed to have macrolide-refractory M. pneumoniae pneumonia. Despite the combination treatment of antimicrobial and anti-inflammatory agents, she showed persistent fever, hepatosplenomegaly, and thrombocytopenia. Secondary HLH associated with M. pneumoniae should be considered if unexplained clinical deterioration is noted in children with macrolide-refractory M. pneumoniae pneumonia.
