Serum vitamin D status and metabolic syndrome: a systematic review and dose-response meta-analysis
- Author:
Kyueun LEE
1
;
Jihye KIM
Author Information
- Publication Type:Original Research
- From:Nutrition Research and Practice 2021;15(3):329-345
- CountryRepublic of Korea
- Language:English
-
Abstract:
RESULTS:The pooled estimates (95% CI) for MetS per 25-nmol/L increment in serum vitamin D concentration were 0.80 (95% CI, 0.76–0.84; I2 = 53.5) in cross-sectional studies, and 0.85 (95% CI, 0.72–0.98; I2 = 85.8) in cohort studies. Similar results were observed, irrespectively of age of study population, study location, MetS criteria, and adjustment factors. There was no publication bias for the dose-response meta-analysis of serum vitamin D concentrations and MetS.
CONCLUSIONS:Dose-response meta-analysis demonstrated that a 25-nmol/L increment in the serum vitamin D concentration was associated with 20% and 15% lower risks of MetS in cross-sectional studies and cohort studies, respectively.
