A case of minimal change nephropathy with malignant thymoma.
- Author:
Hwal Youn LEE
1
;
Hun Hee NA
;
Jeong Ah SHIN
;
Ji Seon LEE
;
Hyun Ji KIM
;
Young Jin YOU
;
Won Do PARK
Author Information
1. Department of Internal Medicine, Inje university, Collage of Medicine Sanggyepaik Hospital, Seoul, Korea. Wondoful1958@sanggyaepaik.ac.kr
- Publication Type:Case Report
- Keywords:
Malignant thymoma;
Nephrotic syndrome
- MeSH:
Azathioprine;
Cyclophosphamide;
Diuretics;
Dyspnea;
Edema;
Humans;
Korea;
Mediastinum;
Middle Aged;
Nephrosis, Lipoid*;
Nephrotic Syndrome;
Oliguria;
Prednisolone;
Pulmonary Fibrosis;
Radiotherapy;
Respiratory Insufficiency;
Thorax;
Thymectomy;
Thymoma*;
Weight Gain
- From:Korean Journal of Medicine
2004;67(4):409-415
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
It is the first case that nephrotic syndrome with malignant thymoma reported in Korea. A 56-year-old man have had generalized edema, weight gain, dyspnea, oliguria for 10 days. At that time, a full blown nephrotic syndrome developed, with minimal change glomerulopathy, A mediastinum mass was shown by the chest X-ray. Thymectomy and palliative radiotherapy was done. In the treatment of nephrotic syndrome, firstly diuretics and prednisolone were given. but the response was poor, so additionally cyclophosphamide and azathioprine were given. After 1 year passed, the patient died of the respiratory failure with pulmonary fibrosis of complication of radiotherapy, without improvement in nephrotic syndrome.
