- Author:
Mulyadi TANJUNG
1
;
Muhammad Fajar ALDIN
;
Tjitjik Srie TJAHJANDARIE
;
Devina Oktari RAHAYU
;
Alfiah Nur Irza GUNAWAN
;
Ratih Dewi SAPUTRI
Author Information
- Publication Type:Original Article
- From:Natural Product Sciences 2021;27(3):172-175
- CountryRepublic of Korea
- Language:English
- Abstract: Sesbagrandiflorain F (1), a novel 2-arylbenzofuran, and two more 2-arylbenzofurans (2-3), were isolated from the stem bark of Sesbania grandiflora L. Based on information HRESIMS data, 1D, and 2D NMR spectra, the structure of 1 was fully assigned. Compounds 1-3 were tested for cytotoxicity in MCF-7 and HeLacells. Compounds 1 and 3 showed moderate activity against MCF-7 cells with an IC50 value of 2.68 and 4.08 µg/mL,respectively. Conversely, all of the isolates were inactive towards HeLa cells.