Unveiling the Functions of the VosA-VelB Target Gene vidD inAspergillus nidulans
10.1080/12298093.2021.1926122
- Author:
Ye-Eun SON
1
;
Hee-Soo PARK
Author Information
1. School of Food Science and Biotechnology, Kyungpook National University, Daegu, Republic of Korea
- Publication Type:RESEARCH ARTICLE
- From:Mycobiology
2021;49(3):258-266
- CountryRepublic of Korea
- Language:English
-
Abstract:
The velvet regulators VosA and VelB are primarily involved in spore maturation and dormancy. Previous studies found that the VosA-VelB hetero-complex coordinates certain target genes that are related to fungal differentiation and conidial maturation in Aspergillus nidulans. Here, we characterized the VosA/VelB-inhibited developmental gene vidD in A. nidulans.Phenotypic analyses demonstrated that the vidD deleted mutant exhibited defect fungal growth, a reduced number of conidia, and delayed formation of sexual fruiting bodies. The deletion of vidD decreased the amount of conidial trehalose, increased the sensitivity against heat stress, and reduced the conidial viability. Moreover, the absence of vidDresulted in increased production of sterigmatocystin. Together, these results show that vidD is required for proper fungal growth, development, and sterigmatocystin production in A. nidulans.
