Immunotherapy-Related Imaging Findings in Patients with Gynecological Malignancies: What Radiologists Need to Know

Author: Luca RUSSO ¹ ; Giacomo AVESANI ; Benedetta GUI ; Charlotte Marguerite Lucille TROMBADORI ; Vanda SALUTARI ; Maria Teresa PERRI ; Valerio Di PAOLA ; Elena RODOLFINO ; Giovanni SCAMBIA ; Riccardo MANFREDI
Author Information

1. UOC Radiologia Generale ed Interventistica Generale, Dipartimento Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Area Diagnostica per Immagini, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
Publication Type:Review Article
From:Korean Journal of Radiology 2021;22(8):1310-1322
CountryRepublic of Korea
Language:English
Abstract: Immunotherapy is an effective treatment option for gynecological malignancies. Radiologists dealing with gynecological patients undergoing treatment with immune checkpoint inhibitors should be aware of unconventional immune-related imaging features for the evaluation of tumor response and immune-related adverse events. In this paper, immune checkpoint inhibitors used for gynecological malignancies and their mechanisms of action are briefly presented. In the second part, patterns of pseudoprogression are illustrated, and different forms of immune-related adverse events are discussed.