A Guillain-Barré Syndrome with Anti-GQ1b and Anti-GT1a Antibodies Positivity Manifesting with Acute Bulbar Palsy and Subsequent Delayed Ophthalmoplegia
10.46518/kjnmd.2020.12.2.36
- Author:
Seonmin YOON
1
;
Jong Seo BAE
;
Byeol-A YOON
;
Jong Kuk KIM
;
Yerim KIM
;
Sang-Hwa LEE
Author Information
1. Department of Neurology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea
- Publication Type:Case Report
- From:
Korean Journal of Neuromuscular Disorders
2020;12(2):36-38
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In Guillain-Barré syndrome (GBS) and its variant, anti-GQ1b antibody has a pathogenic role for ophthalmoplegia. In addition, anti-GT1a antibody is related with lower cranial nerve involvement. This report describes a 60-year-old male patient with GBS manifesting with initially isolated dysphagia and subsequently developed ophthalmoplegia. Both immunoglobulin G type anti-GQ1b and anti-GT1a antibodies were detected in the patient’s serum. A mechanism regarding subsequent involvement of respective cranial nerves remains to be elucidated.
