Aquagenic Urticaria Treated with Omalizumab
10.3904/kjm.2021.96.4.363
- Author:
Ye Jin HA
1
;
So Yeong JUNG
;
Seong Geun LEE
;
Chan Sun PARK
Author Information
1. Department of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea
- Publication Type:3
- From:Korean Journal of Medicine
2021;96(4):363-367
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Aquagenic urticaria is a rare form of physical urticaria in which a 1-2 mm wheal is produced by contact with water. Treatment options include antihistamines, ultraviolet monotherapy, topical barrier creams, and acetylcholine antagonists. Despite these pharmacologic measures, the symptoms are frequently refractory to therapy. Aquagenic urticaria lowers the patient’s quality of life and causes daily discomfort. Recently, a patient with aquagenic urticaria treated with omalizumab was reported. Here, we describe a 22-year-old man with a 3-year history of aquagenic urticaria confirmed by a water immersion test. Because he showed no improvement with antihistamines, the patient began omalizumab treatment and demonstrated an excellent response. This case provides new information for clinicians.
