A Case of Primary Cutaneous Anaplastic Large Cell Lymphoma on the Dorsum of the Hand
- Author:
Chang Il KWON
1
;
Seo Mi Gon JEONG
;
Chi Yeon KIM
Author Information
1. Department of Dermatology, Gyeongsang National University School of Medicine, Jinju, Korea
- Publication Type:Case Report
- From:Korean Journal of Dermatology
2021;59(4):296-298
- CountryRepublic of Korea
- Language:English
-
Abstract:
Primary cutaneous anaplastic large cell lymphoma is primary cutaneous lymphoma that is composed of large lymphoid cells with anaplastic and pleomorphic morphology and expresses the CD30 antigen. Generally, primary cutaneous anaplastic large cell lymphoma is represented by a single, erosive plaque located on the trunk or extremities, but rarely on the dorsum of the hand. A 36-year-old man visited our hospital with a plaque on the dorsum of his left hand for 2 months. The plaque was 6×5 cm in size and violet-colored, with erosion. Histopathological findings showed infiltration of large anaplastic cells in the dermis and subcutaneous fat tissue. Immunohistochemically, it showed positive results for CD3, CD4, and CD30 and negativity anaplastic lymphoma kinase. Imaging examination showed no additional lesions, and the diagnosis was confirmed as primary cutaneous anaplastic large cell lymphoma. The patient was treated with radiation therapy four times and the lesion completely disappeared.
