Chondroid Syringoma: A Clinical and Histopathological Study of 17 Cases
- Author:
Seon Bok LEE
1
;
Seung Dohn YEOM
;
Jeonghyun SHIN
;
Gwang Seong CHOI
;
Ji Won BYUN
Author Information
1. Department of Dermatology, Inha University School of Medicine, Incheon, Korea
- Publication Type:Original Article
- From:Korean Journal of Dermatology
2021;59(3):188-195
- CountryRepublic of Korea
- Language:English
-
Abstract:
Background:Chondroid syringoma (CS) is an uncommon benign neoplasm of the head and neck seen in middle-aged to elderly individuals. Histopathologically, chondroid syringoma displays nests of cuboidal epithelial cells embedded in a matrix. It is classified as both a tubular branching lumina type and a small tubular lumina type and may exhibit a wide range of differentiation and metaplastic changes in the epithelial and stromal components.
Objective:To investigate the correlation between the clinical and histopathologic features of chondroid syringoma.
Methods:We evaluated the electronic medical records, clinical photographs, and histopathological slides of 17 patients diagnosed with chondroid syringoma.
Results:CS in the terminal hair skin tended to have larger lesions (p=0.036). Tumors in terminal hair skin demonstrated significantly more follicular differentiation (p=0.044) than those in the vellus hair skin. CS arising on the scalp tended to have more osseous metaplasia compared to those arising on non-scalp areas (p=0.022).
Conclusion:This study showed that the clinical and histopathological features of CS can differ depending on its location.
