Apocrine Carcinoma of the Breast: The report of 2 cases.
- Author:
Ki Hoon JUNG
1
;
Eun Sook LEE
;
Jeoung Won BAE
;
Bum Hwan KOO
Author Information
1. Department of Surgery, College of Medicine, Korea University, Korea.
- Publication Type:Case Report
- Keywords:
Breast cancer;
Invasive apocine carcinoma
- MeSH:
Breast Neoplasms;
Breast*;
Carcinoma, Ductal;
Epithelium;
Incidence
- From:Journal of the Korean Surgical Society
1997;52(5):755-759
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Apocrine carcinoma is an uncommon, poorly characterized type of breast tumor. The histologic characteristics of apocrine epithelium in malignant breast lesion were first noted by Krompecher(1916), while the first detailed description of an apocrine carcinoma is credited to Ewing in 1928. The reported incidence of apocrine carcinoma is approximately 0.4% of breast cancers. Apocrine carcinoma has distinct histologic and ultrastructural features that distinguish it as a specialized form of infiltrating ductal carcinoma. The finding of a uniform pattern of apocrine differentiation with dense granularity typifying the majority of cells characterizes this variant. We experienced two cases of invasive apocrine carcinoma of the breast and report with a review of the related literature.