Subacute Combined Degeneration with Motor Neuropathy Following Nitrous Oxide Abuse
- Author:
Jin Sung BAE
1
;
Jung Im SEOK
;
Je Wan LEE
Author Information
- Publication Type:Case Report
- From:Journal of the Korean Neurological Association 2021;39(2):82-84
- CountryRepublic of Korea
- Language:Korean
- Abstract: The neurotoxicity of nitrous oxide (N2O) is known to be mainly occurred by interference with action of vitamin B12. A 38-year-old male presented with progressive gait instability after recreational inhalational use of N2O for 2 months. Although spine magnetic resonance image showed typical subacute combined degeneration, nerve conduction study showed motor neuropathy that is atypical findings of vitamin B12 deficiency. This case suggests N2O-induced neuropathy can develop separately from a vitamin B12 deficiency.
