Patterns of Cerebrospinal Fluid Biomarkers and Amyloid Positron Emission Tomography in a Patient with Cerebral Amyloid Angiopathy-Related Inflammation
- Author:
Ji-Yon KIM
1
;
Sungyang JO
;
Yun Jik PARK
;
Hee Jae JUNG
;
Yong Seo KOO
;
Jae-Hong LEE
Author Information
- Publication Type:증례
- From:Journal of the Korean Neurological Association 2021;39(3):172-176
- CountryRepublic of Korea
- Language:Korean
- Abstract: Cerebral amyloid angiopathy-related inflammation (CAA-RI) is a distinct subset of cerebral amyloid angiopathy characterized by the auto-inflammatory response to amyloid-laden small arteries of cerebral cortex and leptomeninges. Clinical features include cognitive-behavioral change, headache, focal neurologic deficits and seizure. Because anti-inflammatory treatments can rapidly relieve neurologic symptoms, early diagnosis is critical. Herein, we report a CAA-RI case with distinct laboratory findings of a decreased cerebrospinal fluid amyloid beta 1-42 level and relatively reduced florbetaben uptake in the focal inflammatory lesion during the acute phase of CAA-RI.
