Neuroleptic Malignant Syndrome Applied with Targeted Temperature Management

Author: So-Yeon YUN ¹ ; Hyun Ji KIM ; Hyo Jin PARK ; Seong Kyu YANG ; Byeongcheon LEE ; Moon-Ku HAN ; Han-Gil JEONG
Author Information

1. Department of Neurology, Seoul National University Bundang Hospital, Seoul National University School of Medicine, Seongnam, Korea
Publication Type:증례
From:Journal of the Korean Neurological Association 2021;39(3):192-196
CountryRepublic of Korea
Language:Korean
Abstract: Neuroleptic malignant syndrome (NMS) is a life-threatening neurologic emergency associated with the use of dopamine receptor-antagonist properties or the rapid withdrawal of dopaminergic medications. NMS is characterized by refractory hyperpyrexia, altered mental state, dysautonomia, and rigor. If hyperpyrexia persists, it can result in multiorgan failure. Herein, we report a case of NMS occurring after metoclopramide administration in a patient with pontine hemorrhage, which was successfully treated with targeted temperature management using a surface cooling device.