The Emerging Role of Fast MR Techniques in Traumatic Brain Injury
10.13104/imri.2021.25.2.76
- Author:
Roh-Eul YOO
1
;
Seung Hong CHOI
Author Information
1. Department of Radiology, Seoul National University Hospital, Seoul, Korea
- Publication Type:Review Article
- From:Investigative Magnetic Resonance Imaging
2021;25(2):76-80
- CountryRepublic of Korea
- Language:English
-
Abstract:
Post-concussion syndrome (PCS) following mild traumatic brain injury (mTBI) is a major factor that contributes to the increased socioeconomic burden caused by TBI.Myelin loss has been implicated in the development of PCS following mTBI. Diffusion tensor imaging (DTI), a traditional imaging modality for the evaluation of axonal and myelin integrity in mTBI, has intrinsic limitations, including its lack of specificity and its time-consuming and labor-intensive post-processing analysis. More recently, various fast MR techniques based on multicomponent relaxometry (MCR), including QRAPMASTER, mcDESPOT, and MDME sequences, have been developed. These MCRbased sequences can provide myelin water fraction/myelin volume fraction, a quantitative parameter more specific to myelin, which might serve as a surrogate marker of myelin volume, in a clinically feasible time. In this review, we summarize the clinical application of the MCR-based fast MR techniques in mTBI patients.
