Thymic carcinoid tumor combined with thymoma--neuroendocrine differentiation in thymoma?.
10.3346/jkms.1993.8.6.458
- Author:
Kyung Ja CHO
1
;
Chang Won HA
;
Jae Soo KOH
;
Jae Il ZO
;
Ja June JANG
Author Information
1. Department of Anatomic Pathology, Korea Cancer Center Hospital, Seoul, Korea.
- Publication Type:Case Reports
- Keywords:
thymus;
carcinoid tumor;
meuroendocrine carcinoma;
thymoma
- MeSH:
Carcinoid Tumor/*pathology;
Humans;
Male;
Middle Aged;
Neoplasms, Multiple Primary/*pathology;
Thymoma/*pathology;
Thymus Neoplasms/*pathology
- From:Journal of Korean Medical Science
1993;8(6):458-463
- CountryRepublic of Korea
- Language:English
-
Abstract:
A carcinoid tumor of the thymus combined with thymoma in a 62-year-old man is described. The mediastinal tumor had been present for 13 years and was associated with pure red cell aplasia. Carcinoid tumor occupied the central two-thirds of the tumor, consisting of nests and trabeculae of monotonous round cells, which ultrastructurally showed many intracytoplasmic dense-core granules. Typical spindle cell type thymoma surrounded the carcinoid area. Clinico-pathologic findings of this unique case suggested that the carcinoid tumor developed within a preexisting thymoma, illustrating a possibility of neuroendocrine differentiation of thymic epithelial cells.
