Herpes Simplex Virus Hepatitis Treated with Acyclovir.
10.12771/emj.2016.39.3.81
- Author:
Beom Jin JEONG
1
;
Hye Jin TAE
;
Young Jun CHO
;
Yeong Mo KANG
;
Eun LEE
;
Sang Jo HAN
;
Jeong Mi SHIN
Author Information
1. Department of Internal Medicine, Seoul Red Cross Hospital, Seoul, Korea. icarus421@hanmail.net
- Publication Type:Case Report
- Keywords:
Herpes simplex virus;
Fulminant hepatic failure;
Acyclovir
- MeSH:
Abdominal Pain;
Acyclovir*;
Anorexia;
Diagnosis;
Female;
Fever;
Hepatitis;
Herpes Simplex*;
Humans;
Immunocompromised Host;
Infant, Newborn;
Jaundice;
Leukopenia;
Liver Failure, Acute;
Mortality;
Nausea;
Pregnant Women;
Simplexvirus*;
Vomiting
- From:The Ewha Medical Journal
2016;39(3):81-84
- CountryRepublic of Korea
- Language:English
-
Abstract:
Herpes simplex viruses (HSVs) are the most common cause of mucocutaneous infections with dissemination to visceral organs. HSV-induced hepatitis is a rare but frequent cause of hepatitis in immunocompromised patients, pregnant women, and newborns. However, diagnosis is often difficult because the clinical features are nonspecific. In addition, the HSV-related mortality rate is high. Signs and symptoms of HSV include fever, anorexia, nausea, vomiting, abdominal pain or tenderness, leukocytopenia, coagulopathy, and an increase in serum transaminase levels without jaundice. We present a patient who did not correspond to the above symptoms, but survived following prompt intravenous high-dose acyclovir provided early in the course of the disease.