Thrombolysis for Prosthetic Mitral Valve Thrombosis: 3 cases report.
- Author:
Man Jong BAEK
1
;
Hyoung Mook KIM
;
In Sung LEE
;
Kyung SUN
;
Kwang Taik KIM
;
Hae Jae KIM
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Korea University College of Medicine.
- Publication Type:Case Report
- Keywords:
Heart valve replacement;
Thrombosis;
Thrombolytic therapy;
Heparin
- MeSH:
Cerebral Infarction;
Female;
Follow-Up Studies;
Heart Atria;
Heparin;
Heparin, Low-Molecular-Weight;
Humans;
Mitral Valve*;
Nadroparin;
Pregnant Women;
Thromboembolism;
Thrombolytic Therapy;
Thrombosis*
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
1999;32(1):70-74
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Thrombosis in valve or left atrium after mechanical mitral valve replacement causes prosthetic valve dysfunction or thromboembolism. Early and adequate therapy is very important but clinically not easy. Thrombolysis can avoid reoperation-related risks and act as an optimal therapy for prosthetic valve thrombosis. This report describes three patients who were treated by using low molecular weight heparin (LMWH) and wafarin. Two patients, including one pregnant woman, had prosthetic valve thrombosis and immobility of valve leaflets, and one patient with recent cerebral infarction due to thromboembolism had thrombus in left atrium. Fraxiparine 0.3 cc (7,500 ICU AXa) was administrated subcutaneously twice or triple daily. At discharge, thrombosis in valve and left atrium were completely or near totally lysed and valve leaflets were normally mobile. During the period of thrombolysis and follow up, there were no complications in all patients.
