Changes in Central Auditory Processing in Patients with Mesial Temporal Lobe Epilepsy after Anterior Temporal Lobectomy with Amygdalohippocampectomy.
10.3988/jcn.2016.12.2.151
- Author:
Su Hyun HAN
1
;
Eun Mi LEE
;
Eun Ju CHOI
;
Han Uk RYU
;
Joong Koo KANG
;
Jong Woo CHUNG
Author Information
1. Department of Neurology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. jkkang@amc.seoul.kr
- Publication Type:Original Article
- Keywords:
central auditory processing disorder;
auditory perceptual disorder;
temporal lobe epilepsy;
hippocampus;
temporal lobectomy;
amygdalohippocampectomy
- MeSH:
Anterior Temporal Lobectomy*;
Audiometry, Pure-Tone;
Auditory Perceptual Disorders;
Epilepsy;
Epilepsy, Temporal Lobe*;
Hearing;
Hippocampus;
Humans;
Intelligence;
Language Development Disorders;
Sclerosis;
Temporal Lobe*
- From:Journal of Clinical Neurology
2016;12(2):151-159
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND AND PURPOSE: This study aimed to determine the effects of anterior temporal lobectomy with amygdalohippocampectomy (ATL-AH) on central auditory processing (CAP) in patients with mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE-HS), and to identify factors that may contribute to the postoperative worsening of CAP. METHODS: Frequency-pattern, duration-pattern, and dichotic tests were performed before and after epilepsy surgery in 22 patients with normal hearing according to pure-tone audiometry. RESULTS: No significant difference in CAP scores was detected between pre- and postoperative tests, but there was a strong association between surgery in the language-dominant temporal lobe and postoperative worsening in the non-dominant-side dichotic test (p<0.05). The probability of a decreased performance in a non-dominant-side dichotic test after surgery was 7.5-fold greater in patients who underwent surgery on the dominant temporal lobe compared with the nondominant temporal lobe. No significant association of postoperative worsening in CAP with the verbal, nonverbal intelligence quotient, or right- or left-side lobectomy was noted. CONCLUSIONS: These results suggest that ATL-AH on the dominant side in patients with mTLE-HS worsens the CAP ability in the non-dominant-side dichotic test.
