The Relationship between Impulsivity and Quality of Life in Euthymic Patients with Bipolar Disorder.
- Author:
Yoon Seok KIM
1
;
Boseok CHA
;
Dongyun LEE
;
Sun Mi KIM
;
Eunsoo MOON
;
Chul Soo PARK
;
Bong Jo KIM
;
Cheol Soon LEE
;
Sojin LEE
Author Information
1. Department of Psychiatry, Gyeongsang National University Hospital, Jinju, Republic of Korea. cbs324@gmail.com
- Publication Type:Original Article
- Keywords:
Bipolar disorder;
Impulsivity;
Quality of life
- MeSH:
Impulsive Behavior;
Bipolar Disorder*;
Diagnostic and Statistical Manual of Mental Disorders;
Humans;
Linear Models;
Psychiatry;
Quality of Life*;
Weights and Measures;
World Health Organization
- From:Psychiatry Investigation
2013;10(3):246-252
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: Bipolar disorder (BD) is characterized by elevated impulsivity, even during periods of remission. Many recovered BD patients have functional impairments, which can lead to poor quality of life (QoL). The aim of this study was to investigate the association between impulsivity and QoL in euthymic BD patients. METHODS: A total of 56 remitted or recovered patients with type I or II BD, diagnosed based on Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria, were recruited. Psychiatrists administered the Clinical Global Impression (CGI) for BD and the Global Assessment of Functioning (GAF) scales and then interviewed the subjects to assess clinical variables. Patients completed the Barratt Impulsiveness Scale (BIS-11) and the World Health Organization Quality of Life Assessment Instrument-Brief Form (WHOQoL-BREF). Pearson correlations, univariate regression analyses, and multiple linear regression analyses were performed. RESULTS: The BIS-11 total score was significantly correlated with the WHOQoL-BREF total score (r=-0.55, p<0.01) and with the WHOQoL-BREF subscales. After controlling for GAF score and other clinical variables, the BIS-11 total score (beta=-0.43, p=0.001) was independently associated with overall QoL. Additionally, the BIS-11 total score was particularly strongly associated with the physical, psychological, and social domains of the multi-dimensional QoL scale. CONCLUSION: Our results suggest that high impulsivity is related to low QoL in euthymic BD patients. Further studies are needed to examine whether interventions for high impulsivity effectively improve QoL in patients with BD.
