Reconstitution of biosynthetic pathway for mushroom-derived cyathane diterpenes in yeast and generation of new "non-natural" analogues.
- Author:
Ke MA
1
;
Yuting ZHANG
1
;
Cui GUO
1
;
Yanlong YANG
1
;
Junjie HAN
1
;
Bo YU
1
;
Wenbing YIN
1
;
Hongwei LIU
1
Author Information
- Publication Type:Journal Article
- Keywords: Biosynthesis; Cyathane-type diterpene; Heterologous expression; Non-enzymatic reaction
- From: Acta Pharmaceutica Sinica B 2021;11(9):2945-2956
- CountryChina
- Language:English
- Abstract: Mushroom-derived cyathane-type diterpenes possess unusual chemical skeleton and diverse bioactivities. To efficiently supply bioactive cyathanes for deep studies and explore their structural diversity,
