The phytochemical, biological, and medicinal attributes of phytoecdysteroids: An updated review.
10.1016/j.apsb.2020.10.012
- Author:
Niranjan DAS
1
;
Siddhartha Kumar MISHRA
2
;
Anusha BISHAYEE
3
;
Eunüs S ALI
4
;
Anupam BISHAYEE
5
Author Information
1. Department of Chemistry, Iswar Chandra Vidyasagar College, Belonia-799 155, Tripura, India.
2. Cancer Biology Laboratory, Department of Zoology, School of Biological Sciences, Dr. Harisingh Gour Central University, Sagar-470 003, Madhya Pradesh, India.
3. Pine View School, Osprey, FL 34229, USA.
4. Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
5. Lake Erie College of Osteopathic Medicine, Bradenton, FL 34211, USA.
- Publication Type:Review
- Keywords:
Anti-inflammatory;
Anticancer activity;
Antidiabetic;
Antimicrobial;
Antioxidant;
Phytoecdysteroids;
Secondary metabolites
- From:
Acta Pharmaceutica Sinica B
2021;11(7):1740-1766
- CountryChina
- Language:English
-
Abstract:
The phytoecdysteroids (PEs) comprise a large group of biologically-active plant steroids, which have structures similar to those of insect-molting hormones. PEs are distributed in plants as secondary metabolites that offer protection against phytophagus (plant-eating) insects. When insects consume the plants containing these chemicals, they promptly molt and undergo metabolic destruction; the insects eventually die. Chemically, ecdysteroids are a group of polyhydroxylated ketosteroids that are structurally similar to androgens. The carbon skeleton of ecdysteroids is termed as cyclopentanoperhydro-phenanthrene with a
