Mitochondrial protein IF1 is a potential regulator of glucagon-like peptide (GLP-1) secretion function of the mouse intestine.

Author: Ying WANG ¹ ; Jiaojiao ZHANG ¹ ; Xinyu CAO ² ; Yaya GUAN ¹ ; Shuang SHEN ² ; Genshen ZHONG ¹ ; Xiwen XIONG ³ ; Yanhong XU ² ; Xiaoying ZHANG ² ; Hui WANG ¹ ; Jianping YE ²
Author Information

1. Henan Key Laboratory of Immunology and Targeted Therapy, Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang 453003, China.
2. Shanghai Diabetes Institute, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 201306, China.
3. School of Forensic Medicine, Xinxiang Medical University, Xinxiang 453003, China.
Publication Type:Journal Article
Keywords: ANT2; ATPIF1; GLP-1; Glucose tolerance; Insulin resistance; L-cells; Microbiota; Mitophagy
From: Acta Pharmaceutica Sinica B 2021;11(6):1568-1577
CountryChina
Language:English
Abstract: IF1 (ATPIF1) is a nuclear DNA-encoded mitochondrial protein whose activity is inhibition of the F