3, 4-seco-Isopimarane and 3, 4-seco-pimarane diterpenoids from Callicarpa nudiflora.
10.1016/S1875-5364(21)60063-8
- Author:
Hang HUANG
1
,
2
;
Chun-Ping TANG
3
;
Chang-Qiang KE
3
;
Ren-Geng SHU
4
;
Yang YE
1
,
5
Author Information
1. State Key Laboratory of Drug Research and Natural Products Chemistry Department, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
2. School of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China.
3. State Key Laboratory of Drug Research and Natural Products Chemistry Department, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
4. School of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China.
5. School of Life Science and Technology, Shanghai Tech University, Shanghai 201210, China. Electronic address: yye@simm.ac.cn.
- Publication Type:Journal Article
- Keywords:
3, 4-seco-Isopimarane;
3, 4-seco-Pimarane;
Callicarpa nudiflora;
DFT calculation;
TDDFT-ECD
- MeSH:
Abietanes/isolation & purification*;
Callicarpa/chemistry*;
Diterpenes/isolation & purification*;
Molecular Structure;
Phytochemicals/isolation & purification*;
Plant Leaves
- From:
Chinese Journal of Natural Medicines (English Ed.)
2021;19(8):632-640
- CountryChina
- Language:English
-
Abstract:
A phytochemical investigation was carried out on the extract of a medicinal plant Callicarpa nudiflora, resulting in the characterization of five new 3, 4-seco-isopimarane (1-5) and one new 3, 4-seco-pimarane diterpenoid (6), together with four known compounds. The structures of the new compounds were fully elucidated by extensive analysis of MS, 1D and 2D NMR spectroscopic data, and time-dependent density functional theory (TDDFT) calculation of electronic circular dichroism (ECD) spectra, and DFT calculations for NMR chemical shifts and optical rotations.
