Microbes as a production host to produce natural activecompounds from mushrooms: biosynthetic pathway elucidationand metabolic engineering.
10.1016/S1875-5364(21)60058-4
- Author:
Li-Yang YANG
1
;
Qiang GONG
1
;
Jian-Quan GUO
2
;
Gui-Lan LI
3
Author Information
1. School of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong 030619, China.
2. School of Public Health, Shanxi Medical University, Taiyuan 030001, China. Electronic address: guojianquan2111922@163.com.
3. School of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong 030619, China. Electronic address: sxtcm_shsys@126.com.
- Publication Type:Review
- Keywords:
Metabolic engineering;
Microbes;
Mushroom;
Natural compound;
Synthetic biology
- MeSH:
Agaricales/chemistry*;
Bacteria/metabolism*;
Biological Products/metabolism*;
Biosynthetic Pathways;
Fermentation;
Metabolic Engineering
- From:
Chinese Journal of Natural Medicines (English Ed.)
2021;19(8):580-590
- CountryChina
- Language:English
-
Abstract:
Mushrooms are abundant in bioactive natural compounds. Due to strict growth conditions and long fermentation-time, microbe as a production host is an alternative and sustainable approach for the production of natural compounds. This review focuses on the biosynthetic pathways of mushroom originated natural compounds and microbes as the production host for the production of the above natural compounds.