Clinical applications of neurolinguistics in neurosurgery.

Peng Wang; Zehao Zhao; Linghao BU; Nijiati Kudulaiti; Qiao Shan; Yuyao Zhou; N U Farrukh Hameed; Yangming Zhu; Lei Jin; Jie Zhang; Junfeng LU; Jinsong WU

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Clinical applications of neurolinguistics in neurosurgery.

Author: Peng WANG ¹ ; Zehao ZHAO ¹ ; Linghao BU ¹ ; Nijiati KUDULAITI ¹ ; Qiao SHAN ¹ ; Yuyao ZHOU ¹ ; N U FARRUKH HAMEED ¹ ; Yangming ZHU ¹ ; Lei JIN ¹ ; Jie ZHANG ¹ ; Junfeng LU ¹ ; Jinsong WU ²
Author Information

1. Glioma Surgery Division, Neurologic Surgery Department, Huashan Hospital, Fudan University, Shanghai, 200040, China.
2. Glioma Surgery Division, Neurologic Surgery Department, Huashan Hospital, Fudan University, Shanghai, 200040, China. jinsong_wu@fudan.edu.cn.
Publication Type:Review
Keywords: dual pathway model; language mapping; neurolinguistics; neurosurgery
MeSH: Brain Mapping; Brain Neoplasms; Humans; Language; Neurosurgery; Neurosurgical Procedures
From: Frontiers of Medicine 2021;15(4):562-574
CountryChina
Language:English
Abstract: The protection of language function is one of the major challenges of brain surgery. Over the past century, neurosurgeons have attempted to seek the optimal strategy for the preoperative and intraoperative identification of language-related brain regions. Neurosurgeons have investigated the neural mechanism of language, developed neurolinguistics theory, and provided unique evidence to further understand the neural basis of language functions by using intraoperative cortical and subcortical electrical stimulation. With the emergence of modern neuroscience techniques and dramatic advances in language models over the last 25 years, novel language mapping methods have been applied in the neurosurgical practice to help neurosurgeons protect the brain and reduce morbidity. The rapid advancements in brain-computer interface have provided the perfect platform for the combination of neurosurgery and neurolinguistics. In this review, the history of neurolinguistics models, advancements in modern technology, role of neurosurgery in language mapping, and modern language mapping methods (including noninvasive neuroimaging techniques and invasive cortical electroencephalogram) are presented.