Monoclonal Gammopathy of Renal Significance (MGRS): Prospects for Treatment in Integrated Chinese and Western Medicine.
10.1007/s11655-021-3446-y
- Author:
Jin-Pu LI
1
;
Ya-Ting DU
1
;
Shen LI
1
;
Xiang-Rong RAO
2
Author Information
1. Department of Nephrology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China.
2. Department of Nephrology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China. raoyisheng@163.com.
- Publication Type:Journal Article
- Keywords:
Chinese medicine;
integrative medicine;
monoclonal gammopathy of renal significance
- From:
Chinese journal of integrative medicine
2021;27(9):643-648
- CountryChina
- Language:English
-
Abstract:
Monoclonal gammopathy of renal significance (MGRS) is a pathological state which presents with a spectrum of renal lesions. MGRS is characterized by pathogenic monoclonal immunoglobulins or light chains produced by a premalignant plasma cell or B cell clone. In view of inadequate understanding in the past, the low detection rate of MGRS often results in poor outcomes and reduces quality of life of patients. Thus, MGRS stands for a group of clinical refractory renal diseases. To date, no standard treatment strategy for MGRS is available. Current consensus suggests a clone-directed approach that aims to eradicate the offending clone, but its long-term prognosis is not clear. In this article, we discuss the diagnostic methods, highlight treatment advances, and introduce integrated Chinese and Western medicine in the management of MGRS.
