Effect of CDK1 Interferes with the Regulation of PLK1, Aurora B and TRF1 on the Proliferation of Leukemia Cells.
10.19746/j.cnki.issn.1009-2137.2021.04.021
- Author:
Hui-Min LI
1
;
Xiang-Xiang CHANG
1
;
Lai-Quan HUANG
2
Author Information
1. Graduate School of Wannan Medical College, Wuhu 241002, Anhui Province, China. Department of Hematology, Yijishan Hospital of Wannan Medical College, Wuhu 241001, Anhui Province, China.
2. Graduate School of Wannan Medical College, Wuhu 241002, Anhui Province, China. Department of Hematology, Yijishan Hospital of Wannan Medical College, Wuhu 241001, Anhui Province, China. E-mail:13675531760@163.com.
- Publication Type:Journal Article
- MeSH:
CDC2 Protein Kinase;
Cell Proliferation;
Female;
Humans;
Leukemia;
Lymphoma, Extranodal NK-T-Cell;
Middle Aged;
Positron Emission Tomography Computed Tomography;
Retrospective Studies
- From:
Journal of Experimental Hematology
2021;29(4):1156-1162
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the clinical characteristics, diagnosis and treatment of 1 case EBV negative extranodal NK/T cell lymphoma (ENKTL) patients.
METHODS:The clinical manifestations, diagnosis and treatment of one case ENKTL patients with EBV negative were analyzed retrospectively.
RESULTS:A 46-year-old woman diagnosed as positive for exosanal NK/T cell lymphoma (EBER
CONCLUSION:EBV negative ENKTL is rare in clinic and easy to be misdiagnosed, so it should be distinguished from peripheral T cell lymphoma. This case was treated with EBV positive ENKTL regimen, with good short-term efficacy.
