Second-generation Sequencing Analysis of Ph
10.19746/j.cnki.issn.1009-2137.2021.04.013
- Author:
Xin LIAO
1
,
2
;
Pin-Li ZOU
1
,
2
;
Ya-Li SHEN
1
,
2
;
Yu-Xia GUO
1
,
2
;
Lin SONG
3
;
Jian-Wen XIA
1
,
4
Author Information
1. Department of Hematology and Oncology, Children's Hospital of Chongqing Medical University
2. Chongqing 400014, China,National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China.
3. National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China,Department of Pharmacy, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
4. Chongqing 400014, China,E-mail: tomahawk6502@sohu.com.
- Publication Type:Journal Article
- MeSH:
Child;
Computational Biology;
Gene Expression Profiling;
Gene Expression Regulation, Neoplastic;
Humans;
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/genetics*;
Signal Transduction;
Software
- From:
Journal of Experimental Hematology
2021;29(4):1101-1108
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To screen the core genes of Philadelphia chromosome positive/Ph like T-cell acute lymphoblastic leukemia (Ph
METHODS:The WES/RNA-seq examination results of Ph
RESULTS:For Ph
CONCLUSION:There are obviously abnormal DNA damage repair pathways in children with Ph
