Value of near-infrared spectroscopy in monitoring intestinal tissue oxygen saturation in preterm infants with hemodynamically significant patent ductus arteriosus: a prospective research.
10.7499/j.issn.1008-8830.2103196
- Author:
Xun-Bin HUANG
1
;
Xiao ZHONG
1
;
Ting LIU
1
;
Guo-Qiang CHENG
;
Hui-Xian QIU
1
Author Information
1. Department of Neonatology, Longgang District Central Hospital of Shenzhen, Shenzhen, Guangdong 518116, China.
- Publication Type:Journal Article
- Keywords:
Near-infrared spectroscopy;
Oxygenation;
Patent ductus arteriosus;
Preterm infant;
Regional oxygen saturation
- MeSH:
Ductus Arteriosus, Patent/diagnostic imaging*;
Humans;
Infant;
Infant, Newborn;
Infant, Premature;
Oxygen;
Prospective Studies;
Spectroscopy, Near-Infrared;
Stroke Volume;
Ventricular Function, Left
- From:
Chinese Journal of Contemporary Pediatrics
2021;23(8):821-827
- CountryChina
- Language:English
-
Abstract:
OBJECTIVES:To study the change in regional oxygen saturation (rSO
METHODS:The preterm infants with patent ductus arteriosus (PDA) who had gestational age <32 weeks and/or birth weight <1 500 g were prospectively enrolled, who were admitted to the Department of Neonatology, Shenzhen Longgang Central Hospital from October 2017 to October 2020.According to the diagnostic criteria for hsPDA, the preterm infants with patent ductus arteriosus (PDA) were divided into two groups: hsPDA and non-hsPDA. According to closure of the ductus arteriosus after oral administration of ibuprofen, the preterm infants in the hsPDA group were subdivided into two groups: hsPDA closure and hsPDA non-closure. Hemodynamic parameters were measured at diagnosis of PDA and after treatment, and the level of intestinal tissue rSO
RESULTS:A total of 241 preterm infants with PDA were enrolled, with 55 infants (22.8%) in the hsPDA group and 186 infants (77.2%) in the non-hsPDA group. There were 36 infants (65%) in the hsPDA closure group and 19 infants (35%) in the hsPDA non-closure group. Compared with the non-hsPDA group, the hsPDA group had a significantly higher left atrial diameter/aortic root diameter ratio and significantly lower left ventricular ejection fraction and fractional shortening (
CONCLUSIONS:hsPDA has an impact on intestinal tissue oxygenation in preterm infants, and continuous monitoring of intestinal tissue rSO
