A prospective randomized controlled study on mouse nerve growth factor in the treatment of global developmental delay in children.
10.7499/j.issn.1008-8830.2106042
- Author:
Jin-Jing YUAN
1
;
De WU
1
;
Wen-Wen WANG
1
;
Jun DUAN
1
;
Xiao-Yan XU
1
;
Jiu-Lai TANG
1
Author Information
1. Department of Pediatric Neurology Rehabilitation Center, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.
- Publication Type:Randomized Controlled Trial
- Keywords:
Child;
Clinical effect;
Global developmental delay;
Mouse nerve growth factor
- MeSH:
Animals;
Epilepsy;
Mice;
Prospective Studies;
Social Skills
- From:
Chinese Journal of Contemporary Pediatrics
2021;23(8):786-790
- CountryChina
- Language:English
-
Abstract:
OBJECTIVES:To study the clinical effect of mouse nerve growth factor (mNGF) in the treatment of children with global developmental delay (GDD).
METHODS:A prospective clinical trial was conducted in 60 children with GDD who were treated in the First Affiliated Hospital of Anhui Medical University between July 2016 and July 2017. These children were randomly divided into two groups: conventional rehabilitation treatment and mNGF treatment group (
RESULTS:Before treatment and after 1.5 months of treatment, there was no significant difference in the developmental quotient (DQ) of each functional area of the Gesell Developmental Scale between the mNGF treatment and conventional rehabilitation treatment groups (
CONCLUSIONS:In children with GDD, routine rehabilitation training combined with mNGF therapy can significantly improve their cognitive, motor, and social abilities.
