Value of airway pH monitoring in determining the association between chronic cough and laryngopharyngeal reflux in children.
- Author:
Yun-Li JIANG
1
;
Dan LI
1
;
Tian-Tian LI
1
;
Bei-Rong WU
1
;
Bing-Ru YIN
1
;
Ai-Qiu LI
1
Author Information
1. Department of Respiratory Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai 200040, China.
- Publication Type:Journal Article
- MeSH:
Child;
Child, Preschool;
Chronic Disease;
Cough/etiology*;
Esophageal pH Monitoring;
Female;
Humans;
Hydrogen-Ion Concentration;
Laryngopharyngeal Reflux;
Male
- From:
Chinese Journal of Contemporary Pediatrics
2021;23(7):713-717
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the value of airway pH monitoring in determining the association between chronic cough and laryngopharyngeal reflux (LPR) in children.
METHODS:A total of 274 children with chronic cough who were treated from January 2016 to December 2019 were enrolled. The DX-pH detection system was used to conduct 24-hour airway pH monitoring. The association between chronic cough and LPR was analyzed.
RESULTS:Among the 274 children, there were 168 boys and 106 girls, with a median age of 62.8 months and a median airway pH value of 7.3. Of all the 274 children, 99 (36.1%) had LPR, and the incidence rate of LPR was 36.9% (62/168) in boys and 34.9% (37/106) in girls (
CONCLUSIONS:LPR is highly associated with the development of chronic cough, and airway pH monitoring may be a safe and effective method for the diagnosis of LPR.
