Advance in research on epigenetic clock/age and its implications.
10.3760/cma.j.cn511374-20200529-00399
- Author:
Li WANG
1
;
Zhiyong QIU
Author Information
1. Beijing Key Laboratory for Children's Nutritionomics, Capital Institute of Pediatric Research, Beijing 100020, China. zqiu007@yahoo.com.
- Publication Type:Journal Article
- MeSH:
Aging/genetics*;
Biomarkers;
DNA Methylation;
Epigenesis, Genetic;
Humans
- From:
Chinese Journal of Medical Genetics
2021;38(8):818-821
- CountryChina
- Language:Chinese
-
Abstract:
The progress of epigenetic research has led to the discovery and confirmation of age-related markers based on DNA methylation. These DNA methylation indices are called "epigenetic clock/age". The concept of "epigenetic clock/age" and the establishment of its evaluation system are helpful to solve some of the long-standing problems in the field of life and medicine. When facing the current global aging, it is of great significance to refer to the comprehensive health parameters to determine the biological age and life span of an individual, and thus to design a plan to slow down the process of life cycle. This paper has summarized the concept and development of "epigenetic clock/age" in recent years.
