Phenotypic and genetic analysis of acute megakaryoblastic leukemia in young children with WT1, MLL-PTD and EVI1 genes.
10.3760/cma.j.cn511374-20200826-00625
- Author:
Liping ZHAO
1
;
Xing CHEN
;
Manjiang LI
;
Huanliang DENG
Author Information
1. Department of Laboratory Medicine/Institute of Medical Genetics, Zhuhai Maternal and Child Health Care Hospital, Zhuhai, Guangdong 519000, China. 1403801042@qq.com.
- Publication Type:Journal Article
- MeSH:
Bone Marrow;
Child;
Child, Preschool;
Chromosome Aberrations;
Humans;
Karyotyping;
Leukemia, Megakaryoblastic, Acute/genetics*;
MDS1 and EVI1 Complex Locus Protein;
Megakaryocytes;
Oncogene Proteins, Fusion;
WT1 Proteins
- From:
Chinese Journal of Medical Genetics
2021;38(7):690-693
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the phenotypic and genetic characteristics of acute megakaryoblastic leukemia (AMKL) in young children accompany by WT1, MLL-PTD and EVI1, in order to improve the diagnosis level of AMKL.
METHODS:EDTA-K
RESULTS:White blood cell count was 12.3× 10
CONCLUSION:Acute megakaryocytic leukemia has unique and complex phenotypic and genetics characteristics.
