Clinical Observation on Antihypertensive Effect of Indapamide(Fludex(R)).
10.4070/kcj.1988.18.3.447
- Author:
Dae Won SOHN
;
Byung Hee OH
;
Young Bae PARK
;
Yun Shik CHOI
;
Jung Don SEO
;
Young Woo LEE
- Publication Type:Original Article
- MeSH:
Blood Glucose;
Blood Pressure;
Chemistry;
Cholesterol;
Creatinine;
Fasting;
Heart Rate;
Humans;
Hypertension;
Indapamide;
Uric Acid
- From:Korean Circulation Journal
1988;18(3):447-453
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The antihypertensive effect of Indapamide(Fludex(R)) was studied in 31 patients of essential hypertension and following results were obtained. 1) Daily dosage was 1mg b.i.d. and total duration of medication was weeks. 2) Mean systolic and diastolic blood pressure declined by 23mmHg(14%) and 18mmHg(17%) respectively. 3) Good or fair controls were achieved in 78% of patients. 4) There was no significant change in heart rate during and after treatment. 5) There were no significant changes in fasting blood sugar, serum creatinine, K+, uric acid, ca++, transaminase and cholesterol levels before and after treatment. 6) In 5 patients transient side effects were observed which resolved spontaneously. In view of these results Indapamide appears to be effective agent for the treatment of mild to moderate hypertension and dose not cause significant change in blood chemistry.
