Preparation and applications of the polymeric micelle/hydrogel nanocomposites as biomaterials.
10.7507/1001-5515.202011024
- Author:
Ni ZENG
1
;
Linrui JIANG
1
;
Qingshan MIAO
1
;
Yunfei ZHI
1
;
Shaoyun SHAN
1
;
Hongying SU
1
Author Information
1. Department of Chemical Engineering, Kunming University of Science and Technology, Kunming 650500, P.R.China.
- Publication Type:Journal Article
- Keywords:
drug carrier;
nanocomposite hydrogels;
polymeric micelle;
wound dressing
- MeSH:
Biocompatible Materials;
Hydrogels;
Micelles;
Nanocomposites;
Polymers
- From:
Journal of Biomedical Engineering
2021;38(3):609-620
- CountryChina
- Language:Chinese
-
Abstract:
Polymeric hydrogels have been widely researched as drug delivery systems, wound dressings and tissue engineering scaffolds due to their unique properties such as good biocompatibility, shaping ability and similar properties to extracellular matrix. However, further development of conventional hydrogels for biomedical applications is still limited by their poor mechanical properties and self-healing properties. Currently, nanocomposite hydrogels with excellent properties and customized functions can be obtained by introducing nanoparticles into their network, and different types of nanoparticles, including carbon-based, polymer-based, inorganic-based and metal-based nanoparticle, are commonly used. Nanocomposite hydrogels incorporated with polymeric micelles can not only enhance the mechanical properties, self-healing properties and chemical properties of hydrogels, but also improve the
