Finite element method simulating bursting process of multi-chamber flexible package infusion bag.
10.7507/1001-5515.202005062
- Author:
Huaijun YUE
1
;
Guanshi WANG
1
;
Wentao JIANG
1
;
Hongbo TAN
2
;
Wenjun LIU
2
;
Zhongqiang ZHU
2
;
Lin ZHU
2
Author Information
1. Department of Mechanics & Engineering, College of Architecture and Environment, Sichuan University, Chengdu 610065, P.R.China.
2. Sichuan Kelun Pharmaceutical Co.Ltd, Chengdu 610500, P.R.China.
- Publication Type:Journal Article
- Keywords:
finite element method;
fluid cavity;
multi chamber infusion bag;
strength of weak welding
- MeSH:
Finite Element Analysis;
Software;
Stress, Mechanical
- From:
Journal of Biomedical Engineering
2021;38(3):556-562
- CountryChina
- Language:Chinese
-
Abstract:
This study aims to overcome the shortcomings such as low efficiency, high cost and difficult to carry out multi-parameter research, which limited the optimization of infusion bag configuration and manufacture technique by experiment method. We put forward a fluid cavity based finite element method, and it could be used to simulate the stress distribution and deformation process of infusion bag under external load. In this paper, numerical models of infusion bag with different sizes was built, and the fluid-solid coupling deformation process was calculated using the fluid cavity method in software ABAQUS subject to the same boundary conditions with the burst test. The peeling strength which was obtained from the peeling adhesion test was used as failure criterion. The calculated resultant force which makes the computed peeling stress reach the peeling strength was compared with experiment data, and the stress distribution was analyzed compared with the rupture process of burst test. The results showed that considering the errors caused by the difference of weak welding and eccentric load, the flow cavity based finite element method can accurately model the stress distribution and deformation process of infusion bag. It could be useful for the optimization of multi chamber infusion bag configuration and manufacture technique, leading to cost reduction and study efficiency improvement.
