A new phenylethanol glycoside from Baphicacanthis Cusiae Rhizoma et Radix.
10.19540/j.cnki.cjcmm.20210429.201
- Author:
Fan XU
1
;
Chang-Xin ZHOU
1
;
Jian-Xia MO
1
;
Li-She GAN
2
Author Information
1. Institute of Modern Chinese Medicine, College of Pharmaceutical Sciences, Zhejiang University Hangzhou 310058, China.
2. Institute of Modern Chinese Medicine, College of Pharmaceutical Sciences, Zhejiang University Hangzhou 310058, China School of Biotechnology and Health Sciences, Wuyi University Jiangmen 529020, China.
- Publication Type:Journal Article
- Keywords:
Baphicacanthis Cusiae Rhizoma et Radix;
chemical constituent;
phenylethanoid glycoside
- MeSH:
Cardiac Glycosides;
Flavonoids;
Glycosides;
Molecular Structure;
Phenylethyl Alcohol;
Rhizome
- From:
China Journal of Chinese Materia Medica
2021;46(18):4749-4756
- CountryChina
- Language:Chinese
-
Abstract:
The 95% ethanol extract of Baphicacanthis Cusiae Rhizoma et Radix was purified by multi-chromatographic methods including microporous resin, silica gel, Sephadex LH-20, and C_(18) reversed-phase column chromatography. Fourteen compounds were isolated and structurally identified, including five phenylethanoid glycosides, five phenylpropanoids, one lupinane triterpene, two alkaloids, and one flavonoid, listed as follows: 2-(4-hydroxy-3-methoxyphenyl)-3-(2-hydroxy-5-methoxyphenyl)-3-oxo-1-propanol B(1), threo-2,3-bis-(4-hydroxy-3-methoxybenzene)-3-methoxypropanol(2), 2-(3-hydroxy-4-methoxyphenyl)-ethanol-1-O-[3,4-O-di-acetyl-(1→3)-O-α-L-rhamnopyranosyl]-β-D-glucopyranoside(3), verbascoside(4), 2″,3″-di-O-acetyl martynoside(5),(+)-pinore-sinol(6), diospyrosin(7), daidzein(8), wiedemannioside B(9), buddlenol A(10), 2″-O-acetyl martyonside(11), lupeol(12), indirubin(13), and tryptanthrin(14). Compound 3 was a new phenylethanoid glycoside, and the other 10 compounds were isolated for the first time from Baphicacanthis Cusiae Rhizoma et Radix except compounds 12, 13, and 14.
