Progress in application of Bletilla striata polysaccharide in novel drug delivery systems and biomaterials.
10.19540/j.cnki.cjcmm.20210528.604
- Author:
Zi-Hao MA
1
;
Jie MA
1
;
Jin-Ying LYU
1
;
Juan HE
1
;
Duo-Wu-Ni JIA
1
;
Xiao YANG
1
;
Yan QU
2
;
Rui ZENG
3
Author Information
1. School of Pharmacy, Southwest Minzu University Chengdu 610041, China.
2. School of Pharmacy, Chengdu University of Traditional Chinese Medicine Chengdu 611137, China.
3. School of Pharmacy, Southwest Minzu University Chengdu 610041, China Science and Technology Department, Southwest Minzu University Chengdu 610041, China.
- Publication Type:Review
- Keywords:
Bletilla striata polysaccharide;
adhesion;
drug delivery;
effect-enhancing and toxicity-reducing;
targeting;
unification of medicines and excipients;
wound dressing
- MeSH:
Biocompatible Materials;
Drug Delivery Systems;
Orchidaceae;
Polysaccharides;
Wound Healing
- From:
China Journal of Chinese Materia Medica
2021;46(18):4666-4673
- CountryChina
- Language:Chinese
-
Abstract:
As the main active ingredient of the orchidaceous herb Bletilla striata, B. striata polysaccharide(BSP) has pharmacological activities such as promoting coagulation, anti-inflammation, anti-oxidation, promoting wound healing, anti-tumor, and immunomodulation, and is biodegradable and non-toxic. Additionally, it has the material properties of suspension thickening, film-forming adhesion, coating and solubilizing, targeting and slow releasing, effect-enhancing and toxicity-reducing, etc., playing the role of unification of medicines and excipients. Therefore, BSP has a wide application prospect in the fields of drug delivery system and trauma repair. This paper reviews the research progress of BSP application in new drug delivery systems and biomaterials based on the related li-terature in recent years, with the aim of providing reference for the further research and application of BSP.
