Systematic review and Meta-analysis of efficacy and safety of acupuncture therapy on hypertensive intracerebral hemorrhage.
10.19540/j.cnki.cjcmm.20210429.501
- Author:
Min WANG
1
;
Min JIA
2
;
Xin-Yang ZHANG
3
;
Wan-Qing DU
4
;
Wei-Wei JIAO
2
;
Qian CHEN
3
;
Lin LEI
3
;
Jia-Yu DUAN
3
;
Chen-Guang TONG
2
;
Wen-Ming YANG
5
;
Zhi-Guo LYU
6
;
Yun-Ling ZHANG
2
;
Xing LIAO
7
Author Information
1. Graduate School,Beijing University of Chinese Medicine Beijing 100029,China Center for Evidence-based Chinese Medicine,Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences Beijing 100700,China.
2. Xiyuan Hospital,China Academy of Chinese Medical Sciences Beijing 100091,China.
3. Graduate School,Beijing University of Chinese Medicine Beijing 100029,China.
4. Graduate School,Beijing University of Chinese Medicine Beijing 100029,China Xiyuan Hospital,China Academy of Chinese Medical Sciences Beijing 100091,China.
5. the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine Hefei 230031,China.
6. the Affiliated Hospital of Changchun University of Chinese Medicine Changchun 130021,China.
7. Center for Evidence-based Chinese Medicine,Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences Beijing 100700,China.
- Publication Type:Systematic Review
- Keywords:
Meta-analysis;
acupuncture;
efficacy;
hypertensive intracerebral hemorrhage;
systematic review
- MeSH:
Acupuncture Therapy;
Humans;
Intracranial Hemorrhage, Hypertensive/therapy*;
Treatment Outcome
- From:
China Journal of Chinese Materia Medica
2021;46(18):4644-4653
- CountryChina
- Language:Chinese
-
Abstract:
To systematically review the efficacy and safety of acupuncture combined with minimally invasive surgery or basic the-rapy in treating hypertensive intracerebral hemorrhage(HICH) patients compared with minimally invasive surgery or basic treatment. In this study, the four Chinese databases, the four English databases, Chinese Clinical Trial Registry and ClinicalTrail.gov, all above were systematically and comprehensively retrieved from the time of database establishment to September 10, 2020. Rando-mized controlled trials(RCTs) were screened out according to inclusion criteria and exclusion criteria established in advanced. The methodological quality of included studies was evaluated by the tool named "Cochrane bias risk assessment 6.1". Meta-analysis of the included studies was performed using RevMan 5.4, and the quality of outcome indicators was evaluated by the GRADE system. Finally, 17 studies were included, involving 1 852 patients with HICH, and the overall quality of the included studies was not high. According to Meta-analysis,(1)CSS score of the group of acupuncture combined with minimally invasive surgery or basic therapy was superior to the group of minimally invasive surgery or basic therapy(MD=-3.50,95%CI[-4.39,-2.61],P<0.000 01);(2)NIHSS score of the group of acupuncture combined with minimally invasive surgery or basic therapy was superior to the group of minimally invasive surgery or basic therapy(MD=-4.78,95%CI[-5.55,-4.00],P<0.000 01);(3)the cerebral hematoma volume of the group of acupuncture combined with minimally invasive surgery or basic therapy was superior to the group of minimally invasive surgery or basic therapy(MD=-4.44,95%CI[-5.83,-3.04],P<0.000 01);(4)ADL score of the group of acupuncture combined with minimally invasive surgery or basic therapy was superior to the group of minimally invasive surgery or basic therapy(MD=20.81,95%CI[17.25,24.37],P<0.000 01);(5)the GCS score of the group of acupuncture combined with minimally invasive surgery or basic therapy was superior to the group of minimally invasive surgery or basic therapy(MD=2.41,95%CI[1.90,2.91],P<0.000 01). The GRADE system showed an extremely low level of evidence for the above outcome indicators. Adverse reactions were mentioned only in two literatures, with no adverse reactions reported. The available evidence showed that acupuncture combined with minimally invasive surgery or basic therapy had a certain efficacy in patients of HICH compared with minimally invasive surgery or basic therapy. However, due to the high risk of bias in the included studies, its true efficacy needs to be verified by more high-quality studies in the future.
