Quality standards of Gleditsiae Spina and its decoction pieces.
10.19540/j.cnki.cjcmm.20210525.305
- Author:
Jin-Miao WANG
1
;
Jun CHI
1
;
Xue JIANG
1
;
Yong LIU
2
;
Zhen-Guo LI
3
;
Er-Ping XU
4
;
Li-Ping DAI
4
;
Zhi-Min WANG
5
Author Information
1. Henan University of Chinese Medicine Zhengzhou 450046, China Engineering Technology Research Center for Comprehensive Development and Utilization of Authentic Medicinal Materials in Henan Province Zhengzhou 450046, China.
2. Engineering Technology Research Center for Comprehensive Development and Utilization of Authentic Medicinal Materials in Henan Province Zhengzhou 450046, China.
3. Henan Institute for Food and Drug Control Zhengzhou 450012, China.
4. Henan University of Chinese Medicine Zhengzhou 450046, China Engineering Technology Research Center for Comprehensive Development and Utilization of Authentic Medicinal Materials in Henan Province Zhengzhou 450046, China Henan Key Laboratory for Modern Research on Zhongjing's Herbal Formulae Zhengzhou 450046, China.
5. Henan University of Chinese Medicine Zhengzhou 450046, China Engineering Technology Research Center for Comprehensive Development and Utilization of Authentic Medicinal Materials in Henan Province Zhengzhou 450046, China Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences Beijing 100700, China.
- Publication Type:Journal Article
- Keywords:
Gleditsiae Spina;
high-performance liquid chromatography(HPLC);
quality standard;
taxifolin;
thin-layer chromatography(TLC)
- MeSH:
Chromatography, High Pressure Liquid;
Drugs, Chinese Herbal;
Quality Control;
Reference Standards
- From:
China Journal of Chinese Materia Medica
2021;46(17):4417-4423
- CountryChina
- Language:Chinese
-
Abstract:
In view of the current inadequate standards for Gleditsiae Spina in the Chinese Pharmacopoeia, this study put forward some new items of the quality standards of Gleditsiae Spina. Thin-layer chromatography(TLC) was performed for identification with the reference substance of taxifolin and the reference material of Gleditsiae Spina as the control. According to the general principles of the Chinese Pharmacopoeia(2020 edition, Vol. 4), the moisture, total ash content, and alcohol-soluble extract of medicinal materials and decoction pieces of Gleditsiae Spina were determined. The content determination method for medicinal materials and decoction pieces of Gleditsiae Spina was established using high-performance liquid chromatography(HPLC), with taxifolin as the quality control index. Based on the determination results of 30 batches of samples of Gleditsiae Spina from different habitats, the draft quality standards of Gleditsiae Spina were developed, which provided suggestions for the revision of the quality standards of Gleditsiae Spina in the Chinese Pharmacopoeia.
