Characteristics and development assumptions of personalized traditional Chinese medicine granules.
10.19540/j.cnki.cjcmm.20210422.302
- Author:
You-Jie WANG
1
;
Yi-Ping LI
2
;
Lan SHEN
3
;
Fei WU
1
;
Yi FENG
1
;
Xiao LIN
3
;
Yan-Long HONG
4
Author Information
1. Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine, Ministry of Education, Shanghai University of Traditional Chinese Medicine Shanghai 201203, China.
2. Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine, Ministry of Education, Shanghai University of Traditional Chinese Medicine Shanghai 201203, China College of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine Shanghai 201203, China.
3. College of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine Shanghai 201203, China.
4. Shanghai Traditional Chinese Medicine Health Service Collaborative Innovation Center, Shanghai University of Traditional Chinese Medicine Shanghai 201203, China.
- Publication Type:Journal Article
- Keywords:
personalized traditional Chinese medicine(TCM) granules;
preparation prediction system;
preparation process commonality;
prescription applicability
- MeSH:
Drugs, Chinese Herbal;
Medicine, Chinese Traditional;
Prescriptions
- From:
China Journal of Chinese Materia Medica
2021;46(15):3746-3752
- CountryChina
- Language:Chinese
-
Abstract:
Personalized traditional Chinese medicine(TCM) granules are positioned as a solid dosage form of TCM decoctions, boasting strong applicability and wide application range. The market prospect of personalized TCM granules is promising in that their preparation by mixed decoction makes up for the shortcoming of formula granules like the Chinese patent medicine granules and classical TCM prescription granules whose components cannot be changed flexibly. However, such factors as insufficient basic research, equipment mismatch, and low process commonality have limited their clinical application. After analyzing the characteristics of perso-nalized TCM granules, their production status, and the bottlenecks restricting their development, this paper pointed out the meaning and key points of developing a generalized preparation process for personalized TCM granules and affirmed the vital roles of the preparation and process prediction system and the on-line detection technology in improving the productivity of granulation. Finally, some assumptions on technology development for solving the specific problems of personalized TCM granules were shared to provide some ideas for the application and development of personalized TCM granules in clinical practice.
