A new labdane-type diterpenoids from Callicarpa nudiflora.
10.19540/j.cnki.cjcmm.20210429.202
- Author:
Li-Li ZHAN
1
;
Wei-Ming HUANG
1
;
Yu-Ting BIAN
1
;
Yi-Guang LI
2
;
Jie CHEN
1
;
Jia LIU
1
;
Jian SHAO
3
Author Information
1. School of Pharmacy, Jiangxi University of Chinese Medicine Nanchang 330004, China.
2. School of Pharmacy, Jiangxi University of Chinese Medicine Nanchang 330004, China Jiangzhong Pharmaceutical Co., Ltd. Nanchang 330004, China.
3. Jiangzhong Pharmaceutical Co., Ltd. Nanchang 330004, China.
- Publication Type:Journal Article
- Keywords:
Callicarpa nudiflora;
chemical constituents;
diterpenoids;
phenylethanoid glycosides
- MeSH:
Callicarpa;
Chromatography, High Pressure Liquid;
Diterpenes;
Molecular Structure;
Plant Leaves
- From:
China Journal of Chinese Materia Medica
2021;46(16):4139-4144
- CountryChina
- Language:Chinese
-
Abstract:
The purpose of the research is to study the bioactive constituents of Callicarpa nudiflora. From the 65% ethanol extract of C. nudiflora leaves, ten compounds were isolated by macroporous adsorption resin, Sephadex LH-20, ODS, silica gel, and preparative HPLC. These compounds were identified as callicapene M6(1), sterebin A(2), isomartynoside(3), crenatoside(4), luteolin-7-O-neohesperidoside(5), apigenin-7-O-β-D-neohesperidoside(6), isoacteoside(7), acteoside(8),(7R)-campneoside I(9), and(7S)-campneoside I(10) on the basis of NMR, HR-ESI-MS, and optical rotation data. Compound 1 was obtained as a new compound. Compounds 2 and 4 were isolated from the genus Callicarpa for the first time. Compounds 9 and 10 were isolated from C. nudiflora for the first time.
